![]() ![]() “We have to do better for people like Mike. “Less than 10% of patients are alive at 5 years from diagnosis, and it’s soul-crushing to tell someone who has gone through treatment that their prognosis isn’t good,” says Dr. “Since circadian rhythms control up to 40% of gene expression in various organs, circadian disruption can significantly contribute to human pathology.” For instance, there is substantial evidence associating circadian disruption with obesity and diabetes, which are pancreatic cancer risk factors. “Our natural circadian cycle has been quite disrupted, particularly among groups such as night shift workers,” he says. Ronnekleiv-Kelly explores how circadian disruptions, such as irregular sleep patterns or irregular food intake, affect pancreatic cancer progression in a mouse model. He is particularly interested in circadian clock proteins which regulate circadian rhythms – what we might call our “internal clock.”ĭr. And even though the survival rates stink, maybe this place can give you more time.”įunds raised from the Faj Squad 5K support surgeon-scientists like Sean Ronnekleiv-Kelly, MD, whose research studies how environmental sensor proteins affect pancreatic cancer. “We need to find a screening tool and we need to find better treatments, and Madison has the team of doctors who work with pancreatic cancer patients and do research. “We felt that the people at UW were as passionate as we are about the pancreas,” says Diane. It was important to the family that the money stay local, but when they learned that there were pancreatic cancer specialists just three hours away at the UW Carbone Cancer Center, they were willing to cross state lines. The first year of the Faj Squad 5K had 350 participants and 50 virtual walkers, with the momentum continuing each year. Within weeks of Mike’s death, his daughters came up with the idea for the Faj Squad 5K, and three and half months later, the family launched the Michael W. So “doing something” meant raising awareness and raising funds for research. Serving as her brother’s patient advocate opened her eyes to the realities of pancreatic cancer. We had to prevent this from happening to someone else.” “My grief took over, and I said - ‘we have to do something.’ We knew Mike wouldn’t want us just sitting around. “It was such a whirlwind, I didn’t even know what to do,” Diane says. Mike’s siblings, Diane Rambousek and Thomas Oglesby, channeled their grief by finding a way to honor their brother’s memory. He sought treatment in Iowa and lived long enough to see Shannon get married, but the cancer was far more aggressive than predicted. Mike was diagnosed with pancreatic cancer on Novemand was given 16 months to live. “Faj” is what Brittany Oglesby and Shannon Huber affectionately called their dad, Mike Oglesby. Though it’s rare to find an Iowa Hawkeye who will show love for the Wisconsin Badgers, the “Faj Squad” is ready to give up the black and gold for a little Badger red and white when it comes to supporting pancreatic cancer research. Mike Oglesby dances with his daughter Shannon at her wedding. ![]()
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